Posted 2 years ago by Wales Gene Park
ABC-07: A trial looking at stereotactic body radiotherapy and chemotherapy for people with locally advanced bile duct cancer The purpose of the ABC-07 trial is examine whether adding radiotherapy called Stereotactic Body Radiotherapy (SBRT) to chemotherapy will improve the outcome for patients with locally advanced biliary tract cancer that are unfit for surgery. All patients will receive 6 cycles of chemotherapy and then they will receive either 5 fractions of SBRT or 2 more cycles of chemotherapy depending on which treatment they are randomised to. Initially we plan to undertake a feasibility phase to see if it is possible to recruit patients into the trial and then we will continue with the randomised phase II study. Patients recruited during this feasibility stage will be included in the analysis of the full randomised phase II study.