TRACERx Renal CAPTURE Sub-study (TRACERxRenal)

 Rare Kidney Cancers / Posted 4 weeks ago

Summary

TRACERx Renal: This is a translational study, which, aims to develop prognostic and predictive biomarkers for patients with renal cell carcinoma (RCC).

CAPTURE Sub-study: Covid-19 antiviral response in a pan-tumour immune monitoring study

  • Inclusion Criteria :
    • Age 18- years or older
    • Patients with histopathologically confirmed renal cell carcinoma, or suspected renal cell carcinoma, proceeding to neoadjuvant therapy and/or nephrectomy/metastasectomy, or identified as having progressive disease
    • Or in patients undergoing nephrectomy for non-malignant disease
    • Medical and/or surgical management in accordance with national and/or local guidelines
    • Written informed consent
    • **CAPTURE sub-study Inclusion criteria:**
    • Documented informed consent
    • Age 18 years or older
    • Confirmed cancer diagnosis (irrespective of cancer type, disease burden or treatment)
    • Group A: Suspected infection with SARS-CoV-2 or positive test for SARS-CoV-2
    • Group B: no clinical indication to test for SARS-CoV-2 (by current Trust guidelines*) or tested negative for SARS-CoV-2
    • Group C: Volunteers without cancer with SARS-CoV-2 (symptomatic and asymptomatic) and those without clinical indication (current national guidelines*) for SARS-CoV-2 testing or tested negative for SARS-CoV-2
  • Exclusion Criteria :
    • Any concomitant medical or psychiatric problems which, in the opinion of the investigator, would prevent completion of treatment or follow-up
    • Medical or psychological condition that would preclude informed consent
    • Lack of adequate tissue
  • Study start date : February 5, 2012
  • Study end date : September 1, 2023
  • Wales-Based Study Contact : Please speak to your clinician
  • Principal Investigator : Samra Turajlic (Royal Marsden NHS Foundation Trust)
Contact details

Dr Sarah Rudman, Guy's & St Thomas Hospital, Great Maze Pond, London.London,England,SE1 9RT  Show Phone Number eleanor.carlyle@rmh.nhs.uk

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